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[根据全身辐射测量和活化分析研究铀中毒时的碘代谢]

[Iodine metabolism in uranium poisoning according to whole-body radiometry and activation analysis].

作者信息

Malenchenko A F, Seregin V V, Kuz'mina T S, Iaroshevich A A

出版信息

Farmakol Toksikol. 1976 Nov-Dec;39(6):722-5.

PMID:1024841
Abstract

Experiments on rats showed that in chronic uranium poisoning the value of the intrathyroid iodine pool changed and time-dependent radioiodine recirculation relationship between the thyroid and the organism was upset. The process of the thyroid adaptation is a complex one, viz. the hormonal capacity of the organism being kept up through an increase in the mass of the thyroid as well as by a higher rate of iodine exchange.

摘要

对大鼠的实验表明,在慢性铀中毒时,甲状腺内碘池的值发生变化,甲状腺与机体之间随时间变化的放射性碘再循环关系被打乱。甲状腺适应过程是一个复杂的过程,即通过甲状腺质量的增加以及更高的碘交换率来维持机体的激素能力。

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