[慢性铀中毒时甲状腺的碘代谢]
[Iodine metabolism in the thyroid gland in chronic uranium poisoning].
作者信息
Malenchenko A F, Seregin V V, Kuz'mina T S
出版信息
Biull Eksp Biol Med. 1976 Aug;82(8):943-5.
PMID:67862
Abstract
The exchange of radioactive and stable iodine was studied for 21 days after the I131 injection in the thyroid gland and the blood of rats against the background of chronic uranium intoxication. The latter was accompanied by a decrease in the number of iodine-transport loci of the gland, as well as of the value of the intrathyroid iodine pool and of the stable iodine concentration in the thyroid tissue. The compensatory reaction of the thyroid gland was expressed in the increase of its mass and the rate of the thyroid metabolism as well.
摘要
在慢性铀中毒背景下，对注射I131后的大鼠甲状腺和血液中放射性碘与稳定性碘的交换进行了21天的研究。这伴随着甲状腺碘转运位点数量的减少，以及甲状腺内碘池的值和甲状腺组织中稳定性碘浓度的降低。甲状腺的代偿反应表现为其质量增加以及甲状腺代谢速率加快。
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