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[慢性铀中毒时甲状腺的碘代谢]

[Iodine metabolism in the thyroid gland in chronic uranium poisoning].

作者信息

Malenchenko A F, Seregin V V, Kuz'mina T S

出版信息

Biull Eksp Biol Med. 1976 Aug;82(8):943-5.

PMID:67862
Abstract

The exchange of radioactive and stable iodine was studied for 21 days after the I131 injection in the thyroid gland and the blood of rats against the background of chronic uranium intoxication. The latter was accompanied by a decrease in the number of iodine-transport loci of the gland, as well as of the value of the intrathyroid iodine pool and of the stable iodine concentration in the thyroid tissue. The compensatory reaction of the thyroid gland was expressed in the increase of its mass and the rate of the thyroid metabolism as well.

摘要

在慢性铀中毒背景下,对注射I131后的大鼠甲状腺和血液中放射性碘与稳定性碘的交换进行了21天的研究。这伴随着甲状腺碘转运位点数量的减少,以及甲状腺内碘池的值和甲状腺组织中稳定性碘浓度的降低。甲状腺的代偿反应表现为其质量增加以及甲状腺代谢速率加快。

相似文献

1
[Iodine metabolism in the thyroid gland in chronic uranium poisoning].[慢性铀中毒时甲状腺的碘代谢]
Biull Eksp Biol Med. 1976 Aug;82(8):943-5.
2
[Iodine metabolism in uranium poisoning according to whole-body radiometry and activation analysis].[根据全身辐射测量和活化分析研究铀中毒时的碘代谢]
Farmakol Toksikol. 1976 Nov-Dec;39(6):722-5.
3
[Effect of uranium on iodine metabolic kinetics in the thyroid gland (short-term intervals)].[铀对甲状腺碘代谢动力学的影响(短期间隔)]
Farmakol Toksikol. 1975 May-Jun;38(3):328-31.
4
[The functional state of the thyroid gland in rats with uranium poisoning].[铀中毒大鼠甲状腺的功能状态]
Eksp Med Morfol. 1974;13(3):148-53.
5
[Evaluation of inorganic phase of intrathyroid stage of iodine metabolism by the accumulation of pertechnetate-Tc99 and I-131 in the thyroid gland in 10 and 20 minutes].[通过高锝酸盐-Tc99和I-131在10分钟和20分钟时在甲状腺中的蓄积对碘代谢甲状腺内阶段的无机相进行评估]
Med Radiol (Mosk). 1976 Jun;21(6):7-10.
6
[Analysis of pharmacological actions by means of iodine kinetic constants].[通过碘动力学常数分析药理作用]
Acta Pharm Hung. 1974 Mar;44(1):37-42.
7
Simulated altitude and iodine metabolism in rats. II. Effects of chronic exposure on serum and thyroid iodinated components; effects on blood fractions and some organ weights.大鼠的模拟海拔与碘代谢。II. 长期暴露对血清和甲状腺碘化成分的影响;对血液成分和一些器官重量的影响。
Aerosp Med. 1968 Apr;39(4):365-75.
8
Thyroxine content in the thyroid gland of domestic animals. VI. Iodine binding in thyroid gland tissue using radioautography.家畜甲状腺中的甲状腺素含量。VI. 利用放射自显影术研究甲状腺组织中的碘结合情况。
Endokrinologie. 1973 May;61(2):195-200.
9
[Iodine isotope function test in the iodine saturated thyroid gland].
Med Welt. 1968 Mar 16;11:700-5.
10
[Heterogeneity of intrathyroidal iodine metabolism].
Bull Schweiz Akad Med Wiss. 1971;27(5):335-45.