Brown C H, DeSimone E M
Contemp Pharm Pract. 1980 Fall;3(4):209-15.
Many elderly individuals in skilled nursing facilities (SNFs), afflicted with an array of acute and chronic diseases, may have as many as 20 different prescribed medications administered on a pro re nata (PRN) basis. In this study, 20 SNFs in Indiana were inspected. Data on PRN medications were taken from medical charts to determine the extent of PRN medication use by the patients. From one to 10 PRN medication were prescribed per patient; 47% of the patients had not used any of their PRN medications. Further data are needed to justify PRN medication prescribing and usage and to decrease the potential for hidden medical costs, adverse drug effects, and drug interactions.
许多住在专业护理机构（SNFs）的老年人患有一系列急慢性疾病，可能会按需服用多达20种不同的处方药。在本研究中，对印第安纳州的20家专业护理机构进行了检查。按需服用药物的数据取自病历，以确定患者使用按需服用药物的程度。每位患者按需服用1至10种药物；47%的患者未使用任何按需服用的药物。需要更多数据来证明按需服用药物的处方和使用的合理性，并降低潜在的隐性医疗成本、药物不良反应和药物相互作用。
