Merillon J P, Motte G, Leclerc F J, Azancot A, Gourgon R
Nouv Presse Med. 1976 Apr 23;6(17):1455-7.
The left ventricular systolic pressure-volume diagram has been established before and after infusion of Nitro-prusside, Angiotensin and over post-extrasystolic potentiation on 33 patients, by the simultaneous measure of the aortic pressure and the left ventricular volume. In every case left ventricular dp/dt max. and (dp/dt/Pt) max. have been measured before and during post-extrasystolic potentiation, and in 16 cases after vasomotor therapy. The end-systolic left ventricular pressure-volume ratio appears to be independent of loading modifications--more than dp/dt max. and (dp/dt/Pt) max.--and on the opposite to be a good index of inotropic state alterations.
通过同步测量主动脉压力和左心室容积,建立了33例患者在输注硝普钠、血管紧张素前后以及早搏后增强期的左心室收缩压-容积图。在每种情况下,均在早搏后增强期之前和期间测量左心室dp/dt最大值和(dp/dt/Pt)最大值,16例患者在血管舒缩治疗后进行了测量。收缩末期左心室压力-容积比似乎与负荷改变无关——比dp/dt最大值和(dp/dt/Pt)最大值更无关——相反,它是心肌收缩状态改变的良好指标。