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[二尖瓣狭窄患者红细胞、心肌及肋间肌中磷酸戊糖途径酶的活性]

[Activity of enzymes of pentosephosphate pathway in the erythrocytes, myocardium and intercostal muscle of patients with mitral valve stenosis].

作者信息

Kukhta V K

出版信息

Vopr Med Khim. 1976 May-Jun;22(3):325-8.

PMID:1025894
Abstract

Decrease in activities of glucose-6-phosphate dehydrogenase and transketolase was observed in erythrocytes of patients with mitral stenosis. Development of the disease was accompanied by a further decrease in the enzymatic activity. The activity of the enzymes was increased in myocardium of atrium sinistrum at the IV stadium as compared with the III stadium of the disease. The glucose-6-phosphate dehydrogenase activity was decreased and the transketolase activity was unaltered in intercostal muscle of the patients.

摘要

在二尖瓣狭窄患者的红细胞中观察到葡萄糖-6-磷酸脱氢酶和转酮醇酶活性降低。疾病发展伴随着酶活性的进一步降低。与疾病的III期相比,IV期左心房心肌中酶的活性增加。患者肋间肌中葡萄糖-6-磷酸脱氢酶活性降低,转酮醇酶活性未改变。

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