Desiatskova R G, Rozina E E, Antiushina T A, Andzhaparidze O G
Vopr Virusol. 1976 Nov-Dec(6):674-9.
Teratogenic properties of rubella virus circulating in the Soviet Union were studied in animal experiments. After inoculation of the virus to white rats on the 5th day of pregnancy, an increased number of resorptions, a decrease in the number and weight of the embryos were observed. In some rats hydramnion was observed. The newborn rats of the infected mothers showed a higher lethality and some delay in weight gain as compared to the control animals, as well as hydrocephaly and microcephaly (2.2%). Persistence of rubella virus hemagglutination-inhibiting antibody in many infected rats and their progeny was established. The results indicate that the national s-rains of rubella virus affect the course of pregnancy and development of progeny in white rats.
在动物实验中研究了苏联境内风疹病毒的致畸特性。在怀孕第5天给白鼠接种该病毒后，观察到吸收增加、胚胎数量和重量减少。在一些大鼠中观察到羊水过多。与对照动物相比，受感染母亲的新生大鼠显示出更高的致死率和体重增加延迟，以及脑积水和小头畸形（2.2%）。确定了许多受感染大鼠及其后代中存在风疹病毒血凝抑制抗体。结果表明，苏联风疹病毒株会影响白鼠的妊娠过程和后代发育。
