缩瞳剂对清醒夜猴眼压的影响。
The effect of miotics on the intraocular pressure of conscious owl monkeys.
作者信息
Lamble J W, Lamble A P
出版信息
Invest Ophthalmol. 1976 Oct;15(10):848-51.
The intraocular pressure of conscious, unsedated owl monkeys (Aotus trivirgatus) was measured with an applanation tonometer. Untreated eyes of the conscious animals were found to have higher values than those reported for owl monkeys anesthetized with pentobarbitone. Locally applied pilocarpine, carbachol, and oxotremorine gave concentration-related reduction in pressure, oxotremorine being the most potent and having longer duration of effect than the other compounds. Slight reductions were also observed with aceclidine and R. S. 86. These results are discussed in relation to the effects of miotics in man.
用压平眼压计测量清醒、未麻醉的夜猴（Aotus trivirgatus）的眼压。发现清醒动物未经治疗的眼睛眼压值高于用戊巴比妥麻醉的夜猴所报道的值。局部应用毛果芸香碱、卡巴胆碱和氧化震颤素可使眼压呈浓度依赖性降低，氧化震颤素作用最强，且作用持续时间比其他化合物更长。醋甲胆碱和R.S.86也可使眼压略有降低。结合缩瞳剂对人类的作用对这些结果进行了讨论。
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