Lisovskaia I L, Volkova R I, Pozin E Ia, Markosian R A
Biull Eksp Biol Med. 1976 Aug;82(8):940-3.
The effect of low KCN concentrations (5-10(4) M) on the ADP-induced aggregation of intact and refractory rabbit platelets was studied. KCN did not change the aggregation of the intact platelets, but stimulated that of the refractory platelets. The effect of the inhibitor stimulating the aggregation was not connected with the release of additional amounts of ADP. A different sensitivity of the aggregation capacity of the intact and refractory cells to the partial inhibition of metabolism was discussed in terms of the suggested earlier "calcium" model of autoregulation of platelet aggregation.
研究了低浓度氰化钾（5 - 10⁻⁴M）对完整和难反应性兔血小板由二磷酸腺苷（ADP）诱导的聚集作用的影响。氰化钾不改变完整血小板的聚集，但刺激难反应性血小板的聚集。抑制剂刺激聚集的作用与额外量的ADP释放无关。根据先前提出的血小板聚集自动调节的“钙”模型，讨论了完整细胞和难反应性细胞聚集能力对代谢部分抑制的不同敏感性。
