Urazaeva L G
Farmakol Toksikol. 1976 May-Jun;39(3):316-9.
Tests conducted on mice demonstrated that methylmethionine-sulfonium chloride (vitamin U) is capable of lowering the permeability of the skin capillaries following the action of stimulants. It greatly potentiates the antiphlogistic effect of acetylsalicylic acid, this action being more pronounced with vitamin U administered one hour before intake of acetlsaliclic acid than when both are taken simultaneously. Given in a dose of 1000 mg/kg vitamin U helps reduce exudation in aseptic serosites in rats. The antiphlogistic effect of vitamin U comes in conjunction with its ability to exercise a protective action against lesion of the gastric mucosa produced by acetylsalicylic acid.
对小鼠进行的试验表明,氯化甲基蛋氨酸(维生素U)在兴奋剂作用后能够降低皮肤毛细血管的通透性。它能大大增强乙酰水杨酸的抗炎作用,在摄入乙酰水杨酸前一小时给予维生素U时,这种作用比两者同时服用时更为明显。以1000毫克/千克的剂量给予维生素U有助于减少大鼠无菌性浆膜炎中的渗出。维生素U的抗炎作用与其对乙酰水杨酸所致胃黏膜损伤的保护作用相关。