Klimenko A I, Khints R
Vopr Med Khim. 1976 Jul-Aug;22(4):547-51.
By means of polyacrylamide gel disc electrophoresis heterogeneity, electrophoretic mobility and relative content of different fractions of histones in nuclei of liver cells were studied in gonadectomized Wistar rats and in castrated in intact animals, administered with testosteone propionate. In all the experiments a significant conservatism of histone proteins was found in postnatal development. In animals, treated with the endocrine preparations, the age peculiarities were shown to reflect the quanitative proportion of different histone fractions.
通过聚丙烯酰胺凝胶圆盘电泳法，研究了去性腺的Wistar大鼠以及对完整动物进行阉割并给予丙酸睾酮后的动物肝细胞细胞核中组蛋白不同组分的异质性、电泳迁移率和相对含量。在所有实验中，均发现组蛋白在出生后的发育过程中具有显著的保守性。在内分泌制剂处理的动物中，年龄特点反映了不同组蛋白组分的定量比例。
