Ivanov V V
Vopr Med Khim. 1976 Nov-Dec;22(6):835-8.
Administration of serotonin into animals and incubation of serotonin with homogenates stimulated disulphide reductase in liver and spleen tissues. The effect of serotonin in vivo was probably mediated by liberation of catecholamines; it was eliminated by pyrilene and reserpine. The reflex mechanisms of catecholamines liberation were mediated by serotonin through serotonin-receptors of T-type. Alteration in the disulphide reductase activity correlated with the increased content of thiols after administration of serotonin.
给动物注射血清素以及将血清素与匀浆一起孵育可刺激肝脏和脾脏组织中的二硫还原酶。血清素在体内的作用可能是由儿茶酚胺的释放介导的；它可被吡苄明和利血平消除。儿茶酚胺释放的反射机制是由血清素通过T型血清素受体介导的。血清素给药后，二硫还原酶活性的改变与硫醇含量的增加相关。
