[Effect of diet with high fat content on lipogenesis in the liver, lipid composition and lipoprotein spectrum of blood].

Content of lipids and lipoprotein composition in blood did not reflect the intensity of lipogenesis in liver tissue of rats, which were kept on diets with high content of vegetable or animal fats. Both diets with excess of fat increased the rate of acetylation reaction in synthesis of glycerides and esterification of free cholesterol in liver tissue. In this case secretion of synthesized lipids into blood was decreased. Excess of vegetable oil, as distinct from animal fat, decreased the content of glycerides, pre-beta and beta-lipoproteins in blood and activated the synthesis of free cholesterol in liver tissue.