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[热处理脂肪摄入对大鼠血脂和血脂蛋白的影响]

[Effect of the ingestion of thermically treated fat on blood lipids and blood lipoproteins in the rat].

作者信息

Sánchez-Muniz F J, Cuesta C, Rodríguez A, Varela G

出版信息

Rev Esp Fisiol. 1986 Mar;42(1):105-10.

PMID:3715145
Abstract

The effect on rats fed on a diet with 15% solid frying fat (diet B) is compared to the effect of a diet with 15% of the same fat but in the raw state (diet A). After 10 weeks being fed on these diets serum triglycerides, phospholipids, total cholesterol, free cholesterol, esterified cholesterol, high density lipoprotein-cholesterol and free fatty acid levels were checked. Percentage of very low density lipoproteins (VLDL), low density lipoproteins (LDL) and high density lipoproteins as well as the composition of these lipoproteins was determined in parallel. Rats fed on diet B showed a significant increase in phospholipids and a significant decrease in VLDL when compared to those fed on diet A. Phospholipids on LDL decreased significantly in diet B fed rats. The data obtained seem to indicate that the hypercholesterolemic tendency induced by frying fat is neutralized by a decrease in VLDL levels.

摘要

将喂食含15%固态煎炸脂肪的饮食(饮食B)的大鼠的效果与喂食含15%相同脂肪但为生的状态的饮食(饮食A)的效果进行比较。在以这些饮食喂养10周后,检查血清甘油三酯、磷脂、总胆固醇、游离胆固醇、酯化胆固醇、高密度脂蛋白胆固醇和游离脂肪酸水平。同时测定极低密度脂蛋白(VLDL)、低密度脂蛋白(LDL)和高密度脂蛋白的百分比以及这些脂蛋白的组成。与喂食饮食A的大鼠相比,喂食饮食B的大鼠的磷脂显著增加,VLDL显著减少。喂食饮食B的大鼠的LDL上的磷脂显著减少。获得的数据似乎表明,煎炸脂肪诱导的高胆固醇血症倾向通过VLDL水平的降低而被中和。

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