Rönnbäck L
Cytobios. 1976;16(63-64):219-26.
The appearance and accumulation of S 100 protein during postnatal development of rats and rabbit, and during pre- and postnatal development of guinea pig, was studied quantitatively by immunoelectrophoresis. High amounts of S 100 were found in newborn guinea pig brain. In rabbit and rat central nervous systems the content of S 100 rose linearily between the 1st and the 3rd and 4th weeks of postnatal life, respectively. From this later period to the adult animal there was a small increase in the amount of S 100 in rabbit and rat brain. The results of this study are compared with other studies on S 100 accumulation during postnatal development of rat, rabbit and guinea pig, using immunofluorescence and immunoelectron microscopic techniques.
通过免疫电泳定量研究了大鼠、家兔出生后发育过程以及豚鼠出生前和出生后发育过程中S100蛋白的出现和积累情况。在新生豚鼠脑中发现了大量的S100。在家兔和大鼠的中枢神经系统中，S100的含量分别在出生后第1周和第3周、第4周之间呈线性上升。从这一后期到成年动物，家兔和大鼠脑中S100的量有小幅增加。将本研究结果与其他使用免疫荧光和免疫电子显微镜技术对大鼠、家兔和豚鼠出生后发育过程中S100积累情况的研究进行了比较。
