Case R L, Guzzetti P J
Hosp Pharm. 1986 May;21(5):423-6, 431-4, 438.
Hospitals with American Society of Hospital Pharmacists accredited residencies were surveyed to assess the state of the art for adverse drug reaction (ADR) reporting. A majority of hospitals used a concurrent ADR reporting mechanism. Only one-fourth of hospitals assessed the causal relationship between the drug and the ADR, whereas the majority assessed the severity of the ADR. Fifty-eight per cent of hospitals received fewer than seven ADR reports in a 6-month period. Antiinfective agents and central nervous system drugs were most frequently cited as causing ADRs. Various corrective action has been taken to reduce ADRs, including changing drug administration procedures, promoting awareness of ADRs, patient teaching, and drug monitoring.
对拥有美国医院药师协会认可的住院医师培训项目的医院进行了调查，以评估药物不良反应（ADR）报告的现状。大多数医院采用了同步ADR报告机制。只有四分之一的医院评估了药物与ADR之间的因果关系，而大多数医院评估了ADR的严重程度。58%的医院在6个月内收到的ADR报告少于7份。抗感染药物和中枢神经系统药物被最频繁地列为导致ADR的药物。已采取各种纠正措施来减少ADR，包括改变给药程序、提高对ADR的认识、对患者进行教育以及药物监测。
