Chamberlain M A, Stergachis A, Sachse-Bray B, Woodard L, Gibson D
Hosp Pharm. 1986 Aug;21(8):742-7.
Decentralized drug distribution and clinical pharmacy services were implemented on two nursing units, orthopedics and oncology, of a health maintenance organization-owned hospital. The use of targeted high-cost drugs was assessed before and during the decentralized pharmacy services intervention on the experimental units and on a comparison unit. Other assessments included a survey of nurses from the experimental units and surveillance of telephone encounters between the central pharmacy and the experimental units. In the experimental units, there were significant changes in cefazolin therapy for prophylaxis, aminoglycoside therapy, and metoclopramide use from baseline to the intervention periods. Cefazolin use for prophylaxis essentially remained the same in the comparison unit. Telephone encounters decreased substantially from the before- to the during-program period. An increase in the proportion of inappropriately drawn aminoglycoside blood levels was also noted in the during-program period. Decentralized pharmacy services appeared to reduce the cost of targeted drugs and improve communications with the nursing units.
在一家健康维护组织所属的医院，在骨科和肿瘤科这两个护理单元实施了分散式药品分发和临床药学服务。在对实验组和一个对照单元进行分散式药房服务干预之前和期间，评估了靶向高成本药物的使用情况。其他评估包括对实验组护士的调查以及对中心药房与实验组之间电话沟通的监测。在实验组，从基线到干预期，用于预防的头孢唑林治疗、氨基糖苷类治疗和甲氧氯普胺的使用有显著变化。对照单元中用于预防的头孢唑林使用基本保持不变。从项目开展前到开展期间，电话沟通大幅减少。在项目开展期间还注意到，氨基糖苷类血药浓度抽取不当的比例有所增加。分散式药房服务似乎降低了靶向药物的成本，并改善了与护理单元的沟通。
