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海洛因成瘾者的波特氏病

Pott's disease in heroin addicts.

作者信息

Forlenza S W, Axelrod J L, Grieco M H

出版信息

JAMA. 1979 Jan 26;241(4):379-80.

PMID:102808
Abstract

Five cases of tuberculous vertebral osteomyelitis occurred in heroin addicts at St Luke's Hospital Center between 1955 and 1975. All patients were men, and four were between 19 and 33 years of age. In contrast with the indolent onset typical to pyogenic or fungal vertebral osteomyelitis in heroin addicts, patients with Pott's disease had an acute toxic reaction, with fever, back pain, weight loss, and night sweats. Neurologic abnormalities, uncommon with pyogenic or fungal vertebral infection, occurred in all patients with tuberculous involvement of the spine. Roentgenograms of the spine were atypical in four patients, including two with an "ivory vertebra." All patients had involvement of extravertebral sites, and one patient had infection with Mycobacterium tuberculosis and M avium.

摘要

1955年至1975年间,圣卢克医院中心有5例海洛因成瘾者发生结核性脊椎骨髓炎。所有患者均为男性,其中4例年龄在19至33岁之间。与海洛因成瘾者中化脓性或真菌性脊椎骨髓炎典型的隐匿性起病不同,波特氏病患者有急性中毒反应,伴有发热、背痛、体重减轻和盗汗。神经学异常在化脓性或真菌性脊椎感染中不常见,但在所有脊柱结核患者中均有发生。4例患者的脊柱X线片表现不典型,其中2例有“象牙椎”。所有患者均有椎体外部位受累,1例患者感染了结核分枝杆菌和鸟分枝杆菌。

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