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对铜绿假单胞菌菌体抗原和鞭毛抗原的抗体反应(作者译)

[Antibody response to somatic and flagellar antigens of Pseudomonas aeruginosa (author's transl)].

作者信息

Ansorg R, Schmitt W, Schwerk V

出版信息

Med Microbiol Immunol. 1978 Oct 20;165(3):181-9. doi: 10.1007/BF02123175.

DOI:10.1007/BF02123175
PMID:102912
Abstract

Using the indirect fluorescent antibody technique, the production of antiflagellar and antisomatic antibodies in rabbits immunized with different P. aeruginosa strains is measured. After 6 injections of formalinized cultures in graded doses over 3 weeks, the antiflagellar antibodies reach the peak in the 4th to 5th week, followed by a rapid fall. The antisomatic antibodies reacting with native and boiled cells show a plateau-shaped maximum from the 3rd to 5th/6th week and fell slightly up to the 11th week. A significant dissociation of antiflagellar and antisomatic antibodies, however, is not observed. The antisomatic antibodies are less absorbed by protein A (Staph. aureus) than are the antiflagellar antibodies.

摘要

采用间接荧光抗体技术,测定用不同铜绿假单胞菌菌株免疫的家兔中抗鞭毛抗体和抗菌体抗体的产生情况。在3周内分6次注射不同剂量的福尔马林固定培养物后,抗鞭毛抗体在第4至5周达到峰值,随后迅速下降。与天然细胞和煮沸细胞反应的抗菌体抗体在第3至5/6周呈现平台状最大值,并在第11周前略有下降。然而,未观察到抗鞭毛抗体和抗菌体抗体的明显解离。抗菌体抗体比抗鞭毛抗体更不易被蛋白A(金黄色葡萄球菌)吸收。

相似文献

1
[Antibody response to somatic and flagellar antigens of Pseudomonas aeruginosa (author's transl)].对铜绿假单胞菌菌体抗原和鞭毛抗原的抗体反应(作者译)
Med Microbiol Immunol. 1978 Oct 20;165(3):181-9. doi: 10.1007/BF02123175.
2
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Zentralbl Bakteriol Orig A. 1977;237(2-3):280-96.
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引用本文的文献

1
Differentiation of the major flagellar antigens of Pseudomonas aeruginosa by the slide coagglutination technique.用玻片凝集技术鉴别铜绿假单胞菌主要鞭毛抗原
J Clin Microbiol. 1984 Jul;20(1):84-8. doi: 10.1128/jcm.20.1.84-88.1984.

本文引用的文献

1
A proposed antigenic schema for the identification of strains of Pseudomonas aeruginosa.一种用于鉴定铜绿假单胞菌菌株的拟议抗原模式。
J Infect Dis. 1961 Sep-Oct;109:183-93. doi: 10.1093/infdis/109.2.183.
2
[Studies on serodiagnostic differentiation of Pseudomonas aeruginosa with the aid of thermolabile antigens].[借助不耐热抗原对铜绿假单胞菌进行血清学诊断鉴别研究]
Z Immun exp ther. 1958 Jun;115(6):492-508.
3
[O-group determination of Pseudomonas strains by means of slide agglutination].[通过玻片凝集法对假单胞菌菌株进行O群鉴定]
Zentralbl Bakteriol Orig. 1958 Feb;170(8):570-83.
4
[Research on O-antigens of Pseudomonas aeruginosa].[铜绿假单胞菌O抗原的研究]
Z Hyg Infektionskr. 1957;144(3):218-28.
5
Serological typing of Pseudomonas aeruginosa and its cross-infection.铜绿假单胞菌的血清学分型及其交叉感染
Jpn J Exp Med. 1970 Oct;40(5):347-59.
6
Production of antibody against Pseudomonas aeruginosa and its serological typing.抗铜绿假单胞菌抗体的产生及其血清学分型。
Jpn J Exp Med. 1971 Feb;41(1):89-94.
7
Serological properties of Pseudomonas aeruginosa. II. Type-specific thermolabile (flagellar) antigens.铜绿假单胞菌的血清学特性。II. 型特异性不耐热(鞭毛)抗原。
Acta Microbiol Acad Sci Hung. 1970;17(1):35-48.
8
Serological properties of Pseudomonas aeruginosa. I. Group-specific somatic antigens.铜绿假单胞菌的血清学特性。I. 群特异性菌体抗原。
Acta Microbiol Acad Sci Hung. 1966;13(4):295-318.
9
Cell-wall structures of Pseudomonas aeruginosa with immunologic significance: a brief review.具有免疫学意义的铜绿假单胞菌细胞壁结构:简要综述。
J Infect Dis. 1974 Nov;130 Suppl(0):S61-4. doi: 10.1093/infdis/130.supplement.s61.
10
Serological typing of Pseudomonas aeruginosa and several points to be considered.铜绿假单胞菌的血清学分型及几点需考虑的事项。
Jpn J Exp Med. 1974 Feb;44(1):1-12.