Kamyshentsev M V, Blinov M N
Biull Eksp Biol Med. 1976 Oct;82(10):1198-200.
Acetylcholinesterase possessed a different activity in the membranes of young, mature and old human erythrocytes - it was greatest in the mature and least in the old cells. In the young and mature erythrocytes the enzyme existed in the form of 3- and in the old ones in the form of 2-molecular components. The data obtained suggested that the changes in the structural organization of acetylcholinesterase in the red cell membrane had a direct relationship to the aging of these cells.
乙酰胆碱酯酶在年轻、成熟和衰老的人类红细胞膜中具有不同的活性——在成熟红细胞中活性最高,在衰老细胞中活性最低。在年轻和成熟红细胞中,该酶以3分子形式存在,而在衰老红细胞中以2分子形式存在。所获得的数据表明,红细胞膜中乙酰胆碱酯酶结构组织的变化与这些细胞的衰老有直接关系。