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红细胞衰老过程中膜成分的不成比例损失。

Disproportional loss of membrane constituents in the course of erythrocyte aging.

作者信息

Trautsch C, Tannert C, Maretzki D

出版信息

Acta Biol Med Ger. 1981;40(6):743-6.

PMID:7324705
Abstract

Acetylcholine esterase activity and sialic acid content were estimated in human erythrocytes separated according to their densities and after fragmentation in vitro by heating or a combined hyperosmolaric-mechanical stress. In vivo aged cells showed a disproportional loss of both membrane constituents. Fragmentation of erythrocytes in vitro resulted in a proportional loss of acetylcholine esterase activity and sialic acid. Young cells are more prone to fragmentation by heat than older ones.

摘要

对根据密度分离的人体红细胞以及在体外经加热或高渗-机械联合应激破碎后的红细胞,测定了乙酰胆碱酯酶活性和唾液酸含量。体内衰老细胞显示这两种膜成分均不成比例地丢失。红细胞在体外破碎导致乙酰胆碱酯酶活性和唾液酸成比例地丢失。年轻细胞比衰老细胞更易受热破碎。

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