Scotti A, Maggi U, Previtali G
Chir Ital. 1976 Dec;28(6):882-90.
A study was made of anesthesiological and resuscitation problems in 18 patients suffering from drepanocytic anemia. An examination of the results showed that the anesthesiological problems do not so much concern selection of the anesthetic as a knowledge of the physiopathology of this disease, i.e. the tendency to bronchopulmonary complications as a result of the increased viscosity of the blood, the increased mechanical fragility of the erythrocytes, and erythrostasis, with consequent rise of ischaemic necrosis and damage to the various parenchymas. It was also observed that pulmonary complications occurred more frequently in preoperatively transfused patients.
对18例镰状细胞贫血患者的麻醉和复苏问题进行了研究。对结果的检查表明,麻醉问题与其说是麻醉剂的选择,不如说是对这种疾病生理病理学的了解,即由于血液粘度增加、红细胞机械脆性增加和红细胞淤滞导致支气管肺部并发症的倾向,进而导致缺血性坏死增加和各种实质器官受损。还观察到,术前输血的患者肺部并发症发生率更高。