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海恩酮治疗埃及血吸虫病患者

Hycanthone in the treatment of Egyptian bilharzial patients.

作者信息

Gawish N

出版信息

Egypt J Bilharz. 1976;3(1):107-13.

PMID:1029644
Abstract

Hycanthone has a schistosomicidal effect against S. haematobium and S. mansoni present singly or combined in the patient. It is effective in all age groups but better in old and adults than in children and better in females than in males. It gave a cure rate of 60.6% after single intramuscular dose of 3 mg/kg body weight. Second dose after three months gave 94.4% cure rate and a third injection after further two months gave 100% cure rate. So, the drug cannot be used in the treatment of bilharziasis as a single dose course.

摘要

海恩酮对患者体内单独或合并存在的埃及血吸虫和曼氏血吸虫具有杀血吸虫作用。它对所有年龄组均有效,但对老年人和成年人的效果优于儿童,对女性的效果优于男性。单次肌肉注射3mg/kg体重后,治愈率为60.6%。三个月后注射第二剂,治愈率为94.4%,再过两个月注射第三剂,治愈率为100%。因此,该药物不能作为单剂量疗程用于治疗血吸虫病。

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