Thiry P S, Roberge F A
Rev Can Biol. 1976 Dec;35(4):217-38.
This review article is primarily aimed at those researches using the experimental physiological approach and gives a survey of analogs and models of the systemic arterial blood flow. They are presented in increasing order of complexity in two sections: the "lumped" and the "distributed" parameter models. In the first section a brief description is given of the purely resistive, Windkessel and multi-element analogs with emphasis on their use in physiology for estimating several hemodynamic variables. The distributed parameter models, whose central idea is pulse wave propagation along the arterial tree, are then presented in five categories, using a new classification scheme. These categories are based on four criteria derived from the assumptions used in the formulation of the fluid and wall equations. The most recent non-linear models are treated in more detail with their common properteis as well as their particular contribution emphasized. In conclusion it is noted that the distributed parameter models also begin to be used to evaluate physiological variables in the experimental and clinical context and that this trend can only become more important in view of the advances made in the field of biomedical instrumentation.
这篇综述文章主要针对那些采用实验生理学方法的研究,并对体循环动脉血流的模拟物和模型进行了概述。它们在两个部分中按照复杂性递增的顺序呈现:“集总”参数模型和“分布”参数模型。在第一部分中,简要描述了纯电阻、风箱式和多元件模拟物,重点介绍了它们在生理学中用于估计多个血流动力学变量的应用。然后,使用一种新的分类方案,将以脉搏波沿动脉树传播为核心思想的分布参数模型分为五类。这些类别基于从流体和血管壁方程公式化中所使用的假设推导出来的四个标准。对最新的非线性模型进行了更详细的探讨,强调了它们的共同特性以及特殊贡献。总之,需要指出的是,分布参数模型也开始被用于在实验和临床环境中评估生理变量,并且鉴于生物医学仪器领域所取得的进展,这一趋势只会变得更加重要。