Weatherall J A
Health Trends. 1982 Nov;14(4):85-8.
Attempts to reduce the number of children born with congenital malformations may be seen as part of the programmes for rubella immunization and for screening for neural tube defects and chromosome anomalies. The rubella immunization programme in England and Wales has not been accompanied by any appreciable decline in the overall incidence of heart or eye malformations detected at or soon after birth. However, the decline in the incidence of babies born with defects of the central nervous system, and of babies born with Down's syndrome to elderly mothers, indicates that interventive methods of control are achieving changes.
减少先天性畸形患儿出生数量的努力可被视为风疹免疫计划以及神经管缺陷和染色体异常筛查计划的一部分。在英格兰和威尔士，风疹免疫计划实施后，出生时或出生后不久检测到的心脏或眼部畸形的总体发病率并未出现明显下降。然而，中枢神经系统缺陷婴儿以及老年母亲所生唐氏综合征婴儿的发病率下降，表明干预性控制方法正在取得成效。
