Fernell E, Uvebrant P, von Wendt L
Department of Pediatrics II, University of Gothenburg, Sweden.
Childs Nerv Syst. 1987;3(6):350-3. doi: 10.1007/BF00270705.
Based on a survey of the population, which included 202 infants with infantile hydrocephalus those who had had overt hydrocephalus at birth were selected and analyzed with respect to origin and outcome. The present series consisted of 47 infants (23% of the total series), 83% of whom were born at term and 17% before term. In the study period 1967-1982, the prevalence was 0.12/1,000 births. Among infants with maldevelopment of the CNS and/or other organs, the mortality before 2 years of age was 37%, and among the survivors the rate of neurological sequelae was 88%. The corresponding figures for infants with uncomplicated hydrocephalus, i.e., without other maldevelopment, was 20% and 44%, respectively. The prognosis was especially poor for infants born before term. It was concluded that the prognosis was largely determined by maldevelopment affecting the CNS macro- or microarchitecture.
基于一项针对人群的调查，该调查涵盖了202例患有婴儿脑积水的婴儿，选取了出生时患有明显脑积水的婴儿，并对其起源和结局进行了分析。本系列包括47例婴儿（占总系列的23%），其中83%为足月出生，17%为早产。在1967 - 1982年的研究期间，患病率为0.12/1000例出生。在中枢神经系统和/或其他器官发育不良的婴儿中，2岁前的死亡率为37%，在幸存者中神经后遗症的发生率为88%。无并发症脑积水（即无其他发育不良）婴儿的相应数字分别为20%和44%。早产婴儿的预后尤其差。得出的结论是，预后很大程度上由影响中枢神经系统宏观或微观结构的发育不良所决定。
