Colburn P A, Ross M B
Hosp Formul. 1988 May;23(5):448-50, 453-7.
The immunization guidelines for the prevention of hepatitis B virus, pneumococcal pneumonia, and Haemophilus influenza type b, have undergone revision in recent years. The indications, efficacy, and safety of hepatitis B virus vaccine, hepatitis B immune globulin, pneumococcal vaccine, and Haemophilus influenzae type b vaccine are reviewed. The current recommendations for immunization from the Centers for Disease Control's Immunization Practices Advisory Committee are also included in the article. While these products have contributed to decreases in disease, the antibody responses elicited are not always adequate to provide extended protection to the populations at greatest risk of disease. By reviewing the current status and immunizing guidelines, it is hoped that the P & T Committee's task of selecting efficacious, safe, and cost-effective preparations will be made easier.
预防乙型肝炎病毒、肺炎球菌肺炎和b型流感嗜血杆菌的免疫指南近年来已经修订。本文综述了乙肝疫苗、乙肝免疫球蛋白、肺炎球菌疫苗和b型流感嗜血杆菌疫苗的适应证、疗效和安全性。文章还纳入了疾病控制中心免疫实践咨询委员会目前的免疫接种建议。虽然这些产品有助于减少疾病发生，但所引发的抗体反应并不总是足以对疾病高危人群提供长期保护。通过回顾当前状况和免疫指南，希望能使药品和治疗学委员会选择有效、安全且具有成本效益的制剂的工作变得更加容易。
