双胞胎中的白血病：产前和产后因素

Leukemia in twins: antenatal and postnatal factors.

作者信息

Keith L, Brown E R, Ames B, Stotsky M, Keith D M

出版信息

Acta Genet Med Gemellol (Roma). 1976;25:336-41. doi: 10.1017/s0001566000014392.

Abstract

Two factors emerged from a search for obstetric phenomena that might explain concordance of leukemia in both members of a twin pair within days or months of each other: antenatal exposure to ionizing radiation; and antenatal cojoined intrauterine circulation. In addition, antenatal tumor metastasis and chromosomal changes, antenatal or postnatal, may be contributory. Continued observation of reports should be carried out.

摘要

通过寻找可能解释双胞胎中两人在彼此相隔数天或数月内均患白血病的产科现象，发现了两个因素：产前暴露于电离辐射；以及产前联体双胎的宫内血液循环。此外，产前或产后的肿瘤转移和染色体变化可能也有作用。应持续观察相关报告。