Brobmann G F, Mikosch H, Meyer M
Langenbecks Arch Chir. 1976;Suppl:257-61.
The vasoconstrictor effects of strophanthin on mesenteric hemodynamics were studied using mechanical ventricular massage to exclude the cardiac effects of the drug. The administration of a calcium antagonistic compound prior to digitalis, together with and after digitalis application, prevented the vasoconstrictor response completely. From our experimental experience the combination of cardiac glycosides with calcium antagonistic compounds seems rational.
使用机械心室按摩来排除药物的心脏效应,研究了毒毛花苷对肠系膜血流动力学的血管收缩作用。在洋地黄应用之前、同时及之后给予钙拮抗化合物,可完全防止血管收缩反应。根据我们的实验经验,强心苷与钙拮抗化合物联合使用似乎是合理的。