Ayala Hernández I, Martínez González M, Halabe Cherem J
Departamento de Medicina Interna, Hospital de Especialidades del Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, México, D.F.
Rev Gastroenterol Mex. 1998 Oct-Dec;63(4):220-3.
Tuberculosis is frequently the form of presentation of HIV infection, even in patients who have not developed AIDS. Nevertheless, pancreatic affection is rare, and focal pancreatic affection is even rarer.
We present the case of a 49 years old man with antecedents of 25 heterosexual partners and exploratory laparotomy three years before because of an hepatic lesion during which he was multitransfunded. He had a one year history of fever, diaphoresis and abdominal pain, in whom ultrasonography detected an image compatible with pancreatic abscess, so he went through laparotomy for drainage; biopsy reported tuberculosis. He persisted with fever and abdominal pain, and a computed tomography scan demonstrated persistent pancreatic abscess. The determination of HIV antibodies was positive, and the CD4 count in 110/mm3. Antituberculous therapy was started and eight weeks later, the computed tomography showed improvement; also, he had clinical improvement. After a two-years follow up, he remains asymptomatic, only with antiretroviral therapy.
Pancreatic tuberculosis is an infrequent complication of this infection. It is considered the result of the dissemination of the infection from near lymphatic nodes. When needle aspiration of a pancreatic abscess is made, it is necessary to effect a culture in order to diagnose tuberculosis. The recommended treatment comprises a four antifimic scheme for 72 doses followed by a triple intermittent scheme for 60 more doses.
结核病常常是艾滋病毒感染的表现形式,即便在尚未发展为艾滋病的患者中也是如此。然而,胰腺受累情况罕见,局灶性胰腺受累则更为罕见。
我们报告一例49岁男性病例,该患者有25个性伴侣史,三年前因肝脏病变接受了剖腹探查术,术中接受了多次输血。他有一年的发热、多汗和腹痛病史,超声检查发现一个与胰腺脓肿相符的影像,因此他接受了剖腹引流术;活检报告为结核病。他持续发热和腹痛,计算机断层扫描显示胰腺脓肿持续存在。艾滋病毒抗体检测呈阳性,CD4细胞计数为110/mm³。开始抗结核治疗,八周后,计算机断层扫描显示病情好转;同时,他的临床症状也有所改善。经过两年的随访,他仅接受抗逆转录病毒治疗,仍无症状。
胰腺结核是这种感染的罕见并发症。它被认为是感染从附近淋巴结播散的结果。当对胰腺脓肿进行穿刺抽吸时,有必要进行培养以诊断结核病。推荐的治疗方案包括一个72剂的四联抗菌方案,随后再进行一个60剂的三联间歇方案。