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[结核性胰腺脓肿:鉴别诊断及药物治疗的良好反应]

[Tuberculous pancreatic abscess: differential diagnosis and favorable response to medical treatment].

作者信息

Boadas J, Rebasa P, Monill J M, Vallverdú H, Condomines J, Lluís F

机构信息

Servicio de Patología Digestiva, Hospital de la Santa Creu i Sant Pau, Barcelona.

出版信息

Gastroenterol Hepatol. 1996 Mar;19(3):156-8.

PMID:8991659
Abstract

Pancreatic tuberculosis is rare and may present differential diagnostic problems, specially with cancer of the pancreas. An immunocompetent patient with a pancreatic tuberculous abscess whose clinical manifestations were epigastric pain and a toxic syndrome of one month of evolution is presented. A cystic mass was detected on computerized axial tomography in the tail of the pancreas suggestive of irresectable carcinoma because of vascular invasion with negative percutaneous cytologic puncture for malignant cells. The patient was surgically treated with no histologic confirmation of malignancy. A second laparotomy was performed at 6 months since spontaneous size reduction, external pancreatic fistula with miliary peritoneal dissemination and biopsy compatible with tuberculous granulomas was found. Staining for resistant acid-alcohol bacilli were always negative. Medical treatment achieved complete disappearance of the pancreatic tumor in one year.

摘要

胰腺结核较为罕见,可能会带来鉴别诊断问题,尤其是与胰腺癌的鉴别。本文报告了一例免疫功能正常的患者,患有胰腺结核脓肿,临床表现为上腹部疼痛和持续一个月的中毒症状。计算机断层扫描显示胰腺尾部有一个囊性肿块,由于血管侵犯提示为不可切除的癌,经皮细胞学穿刺未发现恶性细胞。患者接受了手术治疗,但未得到恶性肿瘤的组织学证实。6个月后,由于肿块自发缩小,进行了第二次剖腹手术,发现有胰腺外瘘伴粟粒性腹膜播散,活检结果与结核性肉芽肿相符。抗酸酒精杆菌染色始终为阴性。药物治疗使胰腺肿瘤在一年内完全消失。

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