Padolecchia R, Puglioli M, Ragone M C, Romani A, Collavoli P L
Section of Neuroradiology, S. Chiara Hospital, Pisa University, Italy.
AJNR Am J Neuroradiol. 1999 Apr;20(4):565-7.
Intraarterial fibrinolysis was performed in three patients with acute central retinal artery occlusion using recombinant tissue plasminogen activator as a fibrinolytic agent. In two cases the ophthalmic artery was selectively catheterized, and in the other a thrombolytic drug was infused into the ophthalmic artery by way of the meningeal collaterals. All patients experienced visual improvement. Fibrinolysis can produce better results than obtained from conservative treatment. A good prognosis can be achieved if the treatment starts within the first 4 to 5 hours after occlusion.
对3例急性视网膜中央动脉阻塞患者采用重组组织型纤溶酶原激活剂作为溶栓药物进行动脉内溶栓治疗。2例患者选择性地对眼动脉进行了插管，另1例则通过脑膜侧支将溶栓药物注入眼动脉。所有患者视力均有改善。溶栓治疗比保守治疗能取得更好的效果。如果在阻塞后的最初4至5小时内开始治疗，可获得良好的预后。
