Awaad S, Helmy O, Fahmy A, Naga M A, Hassanene A, Wahsh E
Gaz Egypt Paediatr Assoc. 1976 Jul-Oct;24(3-4):193-208.
Eleven cases of hemophilia were studied for detection of any change in the platelet function. The results showed hyperfunction in 5 cases, normal function in 4, and hypofunction in the remaining two. The hyperfunction of the platelets was shown in the case with acute hemorrhage and it might be a compensation mechanism. The normal function was shown in cases during the quiescent phase. The hypofunction of the platelets was associated with the presence of AHg inhibitor and platelet antibody. Normal function returned after Cortisone administration. It may be postulated that the inhibitor of factor VIII and the platelet antibody are one and the same thing.
对11例血友病患者进行了研究，以检测血小板功能的任何变化。结果显示，5例功能亢进，4例功能正常，其余2例功能减退。血小板功能亢进出现在急性出血的病例中，这可能是一种代偿机制。静止期病例显示功能正常。血小板功能减退与抗血友病球蛋白（AHg）抑制剂和血小板抗体的存在有关。给予可的松后功能恢复正常。可以推测，因子VIII抑制剂和血小板抗体是同一物质。
