Biggins S, Murray A W
513 Parnassus Avenue, Box 0444, Department of Physiology, University of California, San Francisco, San Francisco, California 94143-0444, USA.
Curr Opin Genet Dev. 1999 Apr;9(2):230-6. doi: 10.1016/s0959-437x(99)80034-3.
Sister chromatid cohesion is essential for accurate chromosome segregation during the cell cycle. Newly identified structural proteins are required for sister chromatid cohesion and there may be a link in some organisms between the processes of cohesion and condensation. Proteins that induce and regulate the separation of sister chromatids have also been recently identified. (This review is an updated version of one that was published in Current Opinion in Cell Biology 1998, 10:769-775.)
姐妹染色单体黏连对于细胞周期中染色体的准确分离至关重要。新发现的结构蛋白是姐妹染色单体黏连所必需的,并且在某些生物体中,黏连过程和凝聚过程之间可能存在联系。最近也鉴定出了诱导和调节姐妹染色单体分离的蛋白质。(本综述是发表于《细胞生物学当前观点》1998年第10卷第769 - 775页的一篇综述的更新版本。)