Agababova A A, Karagezian K G
Vopr Biokhim Mozga. 1976;11:129-42.
Sublethal (400) and lethal (1600) doses of roentgen decrease the level of neutral phospholipids of rat brain and increase that of acid phospholipids. With the development of radiation disease the content of free glycerine and glycerophosphate increases and the glycerokinase and glycolytic pathways of glycerophosphate biosynthesis are activated together with the intensification of the direct and reverse reactions catalyzed by glycerophosphate dehydrogenase. The permeability of the artificial bimolecular phospholipid membranes prepared from rat brain phospholipid extracts is significantly increased at the end of the radiation.
亚致死剂量(400伦琴)和致死剂量(1600伦琴)的X射线会降低大鼠大脑中中性磷脂的水平,并提高酸性磷脂的水平。随着放射病的发展,游离甘油和甘油磷酸的含量增加,甘油激酶以及甘油磷酸生物合成的糖酵解途径被激活,同时由甘油磷酸脱氢酶催化的正向和逆向反应也增强。由大鼠脑磷脂提取物制备的人工双分子磷脂膜的通透性在辐射结束时显著增加。