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[腹部局部照射后伴有放射病和明显肠道综合征大鼠的脂质代谢变化。血液和组织磷脂的脂肪酸组成]

[Changes in lipid metabolism in rats with radiation sickness and a pronounced intestinal syndrome following local irradiation of the abdominal region. Fatty acid composition of the blood and tissue phospholipids].

作者信息

Stepanov S A, Iusupova I U, Grozdov S P

出版信息

Radiobiologiia. 1989 Jan-Feb;29(1):60-4.

PMID:2928485
Abstract

Local irradiation of rat abdomen (13.5 Gy) caused similar changes in fatty-acid composition of phospholipids in the liver, thymus and brain, that is: (a) a decrease in the polyunsaturated fatty acid content in 4 h, (b) a hypercompensatory increase in the content of polyunsaturated fatty acids (excluding thymus) in 24 h, the ratio between essential fatty acids and their derivatives being changed towards accumulation of the latter, and (c) a trend toward normalization in 72 h.

摘要

对大鼠腹部进行局部照射(13.5戈瑞)会使肝脏、胸腺和大脑中磷脂的脂肪酸组成发生类似变化,即:(a)4小时内多不饱和脂肪酸含量降低;(b)24小时内多不饱和脂肪酸含量(胸腺除外)出现超代偿性增加,必需脂肪酸与其衍生物的比例朝着后者的积累方向变化;(c)72小时内有恢复正常的趋势。

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