Leigh J A
Department of Microbiology, University of Washington, Seattle, WA 98195-7242, USA.
Curr Opin Microbiol. 1999 Apr;2(2):131-4. doi: 10.1016/S1369-5274(99)80023-X.
Information regarding transcriptional regulation in Archaea has begun to emerge from in vivo genetic studies. Evidence to date suggests a varied repertoire of regulatory mechanisms in Archaea that invokes both bacterial and eukaryal paradigms, as well as some novel features. Overall simplicity of mechanisms may reflect the prokaryotic lifestyle. Sequencing projects suggest the existence of certain classes of regulators, but experimental verification is needed.
