Houssay A B, Arias N H, Davison T A, Epper C E
Acta Physiol Lat Am. 1976;26(3):186-91.
The effect of prostaglandins upon the diffuse hair wave induced by gonadectomy was studied in male C3H mice. The drugs used were Prostaglandin E1 and Prostaglandin F2alpha, tromethamine salt, which were administered twice a day intraperitoneally during 22 days, in daily doses from 1 to 6 micrograms. The animals had their back clipped and were castrated at the beginning of each experiment. At the end of the 22 day experimental period while all the castrated control mice were completely covered by hair, in the castrated prostaglandin treated mice a marked inhibition of the hair growth was noticed.
在雄性C3H小鼠中研究了前列腺素对性腺切除诱导的弥漫性毛发生长的影响。所用药物为前列腺素E1和前列腺素F2α（ tromethamine盐），在22天内每天腹腔注射两次，日剂量为1至6微克。每次实验开始时，将动物背部毛发剪去并进行阉割。在22天的实验期结束时，发现所有阉割对照小鼠的背部毛发完全覆盖，而接受前列腺素治疗的阉割小鼠的毛发生长受到明显抑制。
