[膳食维生素E对红细胞膜唾液酸和丙二醛含量的影响]

[Effect of dietary VE on the contents of salivary acid and MDA in RBC membrane].

作者信息

Wang F, Dong Z, Zhang Y, Chen Y

机构信息

Department of Military Hygiene, Fourth Military Medical University, Xi'an, China.

出版信息

Wei Sheng Yan Jiu. 1997 May;26(3):196-8.

PMID:10325633

Abstract

Vitamin E can protect membrane from the damage of lipid peroxidation, Salivary acid is the residual of carbohydrate on the membrane. To evaluate the effect of dietary VE on salivary acid, the contents of MDA and salivary acid of erythrocyte (RBC) membrane of rats were measured. The rats were fed with different amounts of dietary VE and stayed at different temperatures. The results revealed that the content of salivary acid of RBC membrane reduced markly (P < 0.01) and the content of MDA of RBC membrane was stable (P > 0.05) after the rats were exposed to cold for 10 days. High dietary VE intake increased the content of salivary acid of RBC membrane (P < 0.01). There was no correlation between the content of salivary acid and MDA of RBC membrane. It suggested that dietary VE could raise the content of salivary acid in RBC membrane, but it can not be explained by the reduction of LPO.

摘要

维生素E能保护细胞膜免受脂质过氧化损伤，唾液酸是细胞膜上碳水化合物的残基。为评估日粮维生素E对唾液酸的影响，测定了大鼠红细胞（RBC）膜中丙二醛（MDA）和唾液酸的含量。给大鼠饲喂不同量的日粮维生素E，并置于不同温度下。结果显示，大鼠暴露于寒冷环境10天后，RBC膜唾液酸含量显著降低（P<0.01），而RBC膜MDA含量稳定（P>0.05）。高日粮维生素E摄入量增加了RBC膜唾液酸含量（P<0.01）。RBC膜唾液酸含量与MDA含量之间无相关性。这表明日粮维生素E可提高RBC膜唾液酸含量，但不能用脂质过氧化（LPO）的降低来解释。