el-Sewedy S M, Abdel-Tawab G A, Zaki A M
Trans R Soc Trop Med Hyg. 1978;72(5):529-32. doi: 10.1016/0035-9203(78)90177-3.
Serum alkaline ribonuclease activity and serum albumin concentration were determined in 25 normal children and 59 children with protein-energy malnutrition. The increase in serum ribonuclease was marked in marasmus and marasmic kwashiorkor. The ribonuclease activity dropped significantly after two weeks of treatment and returned to normal by four weeks. In kwashiorkor, serum ribonuclease activity was significantly lower than control and returned to normal after four weeks of treatment. These findings support previous observations that the serum ribonuclease is a good criterion of the nutritional status and indicates that the enzyme activity, particularly when related to serum albumin, is a good prognostic index in this respect.
对25名正常儿童和59名蛋白质 - 能量营养不良儿童测定了血清碱性核糖核酸酶活性和血清白蛋白浓度。在消瘦症和消瘦型夸希奥科病中，血清核糖核酸酶显著升高。治疗两周后，核糖核酸酶活性显著下降，四周后恢复正常。在夸希奥科病中，血清核糖核酸酶活性显著低于对照组，治疗四周后恢复正常。这些发现支持了先前的观察结果，即血清核糖核酸酶是营养状况的良好指标，并表明在这方面酶活性，特别是与血清白蛋白相关时，是一个良好的预后指标。
