Sousa Escandón M A, Picallo Sánchez J A, Argüelles Pintos M, Alonso Alonso P, Alvarez Asensio E, Mateos Colino A
Servicio de Urología, Hospital Comarcal de Monforte, Lugo.
Actas Urol Esp. 1999 Feb;23(2):89-94.
Kaposi's sarcoma is a lymphoproliferative opportunistic tumor associated with acquired immunodeficiency syndrome whose frequency is going down due to the use of combined therapies including proteases and others antivirals. During the last years, it has been postulated that it's origin is in the oncogenic potential of HVH-8; however, for the development of the disease, it's necessary the presence of some coadjuvant factors including immunodeficiency and probably a propicious hormonal status. We practiced a bibliographic review of some recent works related with it's etiology and coadyuvant factors implicated in the development of this neoplasia, phrasing some questions that should be answered in the light of future investigative works.
卡波西肉瘤是一种与获得性免疫缺陷综合征相关的淋巴增殖性机会性肿瘤，由于使用包括蛋白酶和其他抗病毒药物在内的联合疗法，其发病率正在下降。在过去几年中，有人推测其起源于人类疱疹病毒8型的致癌潜力；然而，对于该疾病的发展，一些辅助因素的存在是必要的，包括免疫缺陷以及可能有利的激素状态。我们对一些近期与该肿瘤病因及发展中涉及的辅助因素相关的研究进行了文献综述，提出了一些应根据未来研究工作予以解答的问题。
