Colorado Murguía S, Flores Hernández B, Escobar Moreno A C
Depto. de Consulta Externa de Ginecología Oncológica, Hospital Regional de Especialidades No. 23, Dr. Ignacio Morones Prieto del Instituto Mexicano del Seguro Social, Monterrey, N.L.
Ginecol Obstet Mex. 1999 Feb;67:80-4.
The objective was to evaluate the accuracy of the cytologic study of fine needle aspiration biopsy and to share the authors experiences. A prospective study was done in the Hospital Regional de Especialidades No. 23, Instituto Mexicano del Seguro Social, from March 1996 to June 1997. A solid mammary nodule was diagnosed in 250 women. A fine needle punction was done in all of them. One hundred seven had cysts. The remaining 143 patients were included in this report. The clinical diagnosis was benign pathology in 87 cases and malignancy in 56. They gad a fine needle aspiration and, in those older than 35 years, a mammography was also done. The cytologic result correlated with the clinical diagnosis in 141 cases with an accuracy of 98.61%. There was any false positive result. The mammographic report correlated with the diagnosis in 30.06% of the cases, and do not correlated in 41.96%. All patients with benign pathology had a transoperative biopsy and tumorectomy. Patients with diagnosis of malignancy had a preoperative staging, which showed that 62.06% were in a surgical stage. They had a transoperative biopsy and a modified radical mastectomy. The remaining 37.94% were in a nonsurgical stage, therefore, they were referred for chemotherapy and radiotherapy. In our experience, the cytology by fine needle aspiration biopsy in solid mammary nodules is a diagnostic method with an excellent sensitivity and specificity as well as low morbility and cost.
目的是评估细针穿刺活检细胞学研究的准确性并分享作者的经验。1996年3月至1997年6月在墨西哥社会保障局第23号地区专科医院进行了一项前瞻性研究。250名女性被诊断出有实性乳腺结节。对她们所有人都进行了细针穿刺。其中107人有囊肿。其余143名患者被纳入本报告。临床诊断为良性病变87例,恶性病变56例。她们接受了细针穿刺,35岁以上者还进行了乳房X线摄影。141例细胞学结果与临床诊断相符,准确率为98.61%。无假阳性结果。乳房X线摄影报告与诊断相符的病例占30.06%,不相符的占41.96%。所有良性病变患者均进行了术中活检和肿瘤切除术。诊断为恶性肿瘤的患者进行了术前分期,结果显示62.06%处于手术阶段。她们接受了术中活检和改良根治性乳房切除术。其余37.94%处于非手术阶段,因此被转诊接受化疗和放疗。根据我们的经验,细针穿刺活检对实性乳腺结节进行细胞学检查是一种诊断方法,具有出色的敏感性和特异性,以及低发病率和低成本。