Marucci G, Bondi A, Lorenzini P, Eusebi V
Dipartimento di Oncologia, Sezione di Anatomia, Istologia e Citologica Patologica M. Malpighi, Università di Bologna, Ospedale Bellaria, Via Altura 3, I-40139 Bologna.
Pathologica. 2001 Feb;93(1):15-9.
We report two cases in which fine needle aspiration (FNA) in the breast generated changes histologically mimicking malignant lesions. In both cases a population of giant cells was present; the cells were osteoclast-like in the first case and 'atypical' multinucleated stromal giant cells in the second. The underlying lesion was pseudoangiomatous stromal hyperplasia (PASH) in both cases. The reactive nature was confirmed by retracing the needle tract and by the uneventful follow-up of 7 or 2 years, respectively. We propose that giant cell reaction be included in the list of FNA-generated changes.
我们报告了两例乳腺细针穿刺抽吸（FNA）在组织学上产生类似恶性病变改变的病例。两例均出现了巨细胞群；第一例中的细胞为破骨细胞样，第二例为“非典型”多核间质巨细胞。两例的潜在病变均为假血管瘤样间质增生（PASH）。通过追踪针道以及分别进行7年或2年的无异常随访，证实了其反应性本质。我们建议将巨细胞反应纳入FNA产生的改变列表中。
