Morgan W W, Pfeil K A, Reiter R J, Gonzales E
Brain Res. 1976 Nov 19;117(1):77-84. doi: 10.1016/0006-8993(76)90557-6.
Groups of male golden hamsters and Sprague-Dawley rats were sacrificed at 4-h intervals over a 24-h period. Tryptophan and serotonin (5-HT) were measured in the telencephalon and brain stem and tryptophan was measured in serum. Highly statistically significant changes in tryptophan and 5-HT content were observed over the period of the day. Generally the changes were more clearly defined and were significant to a higher statistical level in the hamster than in the rat. Statistically significant changes were also observed in serum tryptophan. In the hamster the daily changes in serum tryptophan were coincidental with similar changes in tryptophan and 5-HT in the brain stem and tryptophan in the telencephalon. On the other hand, the changes in 5-HT in the hamster telencephalon were not well correlated with changes in tryptophan and serum tryptophan.
在24小时期间，每隔4小时处死一组雄性金黄仓鼠和斯普拉格-道利大鼠。测定端脑和脑干中的色氨酸和血清素（5-HT），并测定血清中的色氨酸。在一天的时间里，观察到色氨酸和5-HT含量有高度统计学意义的变化。一般来说，这些变化在仓鼠中比在大鼠中更明确，且在更高的统计水平上具有显著性。血清色氨酸也观察到有统计学意义的变化。在仓鼠中，血清色氨酸的每日变化与脑干中色氨酸和5-HT以及端脑中色氨酸的类似变化一致。另一方面，仓鼠端脑中5-HT的变化与色氨酸和血清色氨酸的变化没有很好的相关性。
