Khandjian E W, Turian G
Cell Differ. 1976 Oct;5(3):171-88. doi: 10.1016/0045-6039(76)90019-1.
A correlation between release of a nucleic acid protein complex into the external medium and sporangial differentiation was found. Conditions preventing differentiation also stopped the release. Lethal lysis is not involved in this release process. Extracellular nucleic acids are very heterogenous, consisting of nucleotides as well as acid-precipitable nucleic acids. RNA was found to be associated with proteins and a hetero-duplex RNA--DNA associated with this nucleoprotein. Some speculations are presented about possible correlation between the release of nucleoprotein complexes and the intracellular events of differentiation.
发现核酸蛋白复合物释放到外部介质中与孢子囊分化之间存在相关性。阻止分化的条件也会停止释放。致死性裂解不参与此释放过程。细胞外核酸非常异质，由核苷酸以及酸可沉淀核酸组成。发现RNA与蛋白质相关联，并且一种异源双链RNA-DNA与这种核蛋白相关联。针对核蛋白复合物的释放与细胞内分化事件之间可能的相关性提出了一些推测。
