Torda C
J Neurosci Res. 1976;2(3):193-202. doi: 10.1002/jnr.490020303.
The potential for at least partial reversible transition of aggression- and anxiety-type symptomatology suggested searching for a potential biochemical link between subcellular mechanisms involved in the execution of aggression and anxiety. The effects of norepinephrine combined with dopamine and of epinephrine on these two types of behavior were tested. Responses to foot-shock were used to test aggression, extinction of avoidance response was used to test anxiety-type behavior. The results suggested that one of the possible links between the intracerebral processes responsible for execution of aggression- and anxiety-type behaviors is transmethylation of norepinephrine and/or dopamine to epinephrine.
攻击和焦虑型症状至少部分可逆转变的可能性表明，需要寻找参与攻击和焦虑行为执行的亚细胞机制之间潜在的生化联系。测试了去甲肾上腺素与多巴胺联合以及肾上腺素对这两种行为类型的影响。用对足部电击的反应来测试攻击性，用回避反应的消退来测试焦虑型行为。结果表明，负责攻击和焦虑型行为执行的脑内过程之间可能的联系之一是去甲肾上腺素和/或多巴胺向肾上腺素的转甲基作用。
