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[针对对人类无攻击性而选育的挪威大鼠的行为和记忆类型特征]

[Typological features of behavior and memory in Norway rats selected for absence of aggression toward a man].

作者信息

Loskutova L V, Dubrovina N I, Pliusnina I F

机构信息

Institute of Physiology, Institute of Cytology and Genetics, Russian Academy of Sciences, Siberian Division, Novosibirsk.

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 2003 Nov-Dec;53(6):739-45.

Abstract

Features of behavior and retrieval of passive conditioned avoidance on a new and forgotten stimuli were compared in Wistar rats and Norway rats bred for the absence of aggression toward a man. As distinct from white rats, grey rats were characterized by low anxiety and high locomotor exploratory activity in the elevated plus maze and dark-light chamber. Norway rats demonstrated better avoidance performance with active defensive behavioral strategy than Wistar rats. Latent inhibition during conditioning with a previously forgotten situational stimulus was the same in both rat strains. The results are discussed in terms of the use of grey rats as a model for an in-depth analysis of the mechanisms of memory optimization.

摘要

在对人无攻击性的Wistar大鼠和挪威大鼠中,比较了对新刺激和遗忘刺激的被动条件性回避行为及记忆提取的特征。与白鼠不同,灰鼠在高架十字迷宫和明暗箱中表现出低焦虑和高运动探索活动。挪威大鼠采用主动防御行为策略时的回避表现优于Wistar大鼠。两种品系大鼠在对先前遗忘的情境刺激进行条件反射时的潜伏抑制相同。就将灰鼠用作深入分析记忆优化机制的模型进行了讨论。

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