Dilek L, Atalay S, Gumus H, Imamoglu A, Tutar E, Altug N
Department of Pediatric Cardiology, Ankara University, Medical School, Turkey.
Int J Cardiol. 1999 Apr 30;69(1):41-7. doi: 10.1016/s0167-5273(99)00004-2.
Eighteen patients with chronic isolated rheumatic mitral regurgitation aged between 7 and 19 years (mean age +/-SD, 12.69+/-3.47 years) were analyzed with color Doppler imaging. Sixteen patients were performed cardiac catheterization within 24 h. Jets were classified as eccentric and central. Regurgitant jet area and its ratio to left atrial area and body surface area were measured by Doppler color flow imaging. Regurgitant volume and regurgitant fractions were calculated with angiography. There was a good correlation between regurgitant jet area and angiographic grade of mitral regurgitation (P<0.01). The correlation between regurgitant jet area/left atrial area ratios and angiographic grade of mitral regurgitation was limited (P<0.01). There was excellent correlation between regurgitant jet area/body surface area and angiographic regurgitant fraction (r = 0.85; P<0.001). There was also a good correlation between regurgitant jet area and regurgitant fraction (r = 0.82; P<0.001). However, the relation of regurgitant jet area/left atrial area to regurgitant fraction was weak (r = 0.72; P<0.01). In conclusion, the measurement of regurgitant fraction and its ratios to left atrial area and body surface area by color Doppler flow imaging can predict the angiographic severity in children who have even eccentric regurgitant jets.
对18例年龄在7至19岁（平均年龄±标准差，12.69±3.47岁）的慢性单纯风湿性二尖瓣反流患者进行了彩色多普勒成像分析。16例患者在24小时内进行了心导管检查。反流束分为偏心型和中心型。通过多普勒彩色血流成像测量反流束面积及其与左心房面积和体表面积的比值。用血管造影术计算反流容积和反流分数。反流束面积与二尖瓣反流血管造影分级之间存在良好的相关性（P<0.01）。反流束面积/左心房面积比值与二尖瓣反流血管造影分级之间的相关性有限（P<0.01）。反流束面积/体表面积与血管造影反流分数之间存在极好的相关性（r = 0.85；P<0.001）。反流束面积与反流分数之间也存在良好的相关性（r = 0.82；P<0.001）。然而，反流束面积/左心房面积与反流分数之间的关系较弱（r = 0.72；P<0.01）。总之，通过彩色多普勒血流成像测量反流分数及其与左心房面积和体表面积的比值，可以预测即使存在偏心反流束的儿童患者的血管造影严重程度。
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