Stepanova L K, Sergeeva N S, Belaia Iu A
Zh Mikrobiol Epidemiol Immunobiol. 1978 Nov(11):41-7.
The authors obtained a complex antigen from paratyphoid B bacilli containing complete O-, K- and H-antigens. The preparation was nontoxic and was characterised by marked antigenic properties. In intravenous and oral administration it stimulated production of specific O-, K-, and H-antibodies in high titres. Complex paratyphoid B antigen possessed a marked protective activity and provided intense immunity in subcutaneous and oral administration to experimental animals.
作者从含有完整O抗原、K抗原和H抗原的副伤寒杆菌中获得了一种复合抗原。该制剂无毒，具有显著的抗原特性。静脉内和口服给药时，它能刺激产生高滴度的特异性O抗体、K抗体和H抗体。复合副伤寒B抗原具有显著的保护活性，皮下和口服给药时能使实验动物产生强烈的免疫力。
