Stepanova L K, Belaia Iu A, Sergeeva N S, Rubtsov I V, Ageeva V A
Zh Mikrobiol Epidemiol Immunobiol. 1978(12):76-82.
Reactogenic property and immunological efficacy of the paratyphoid preparation containing a complex of O-, K- and H-antigens obtained by single-stage antigens extraction were studied in a limited group of volunteers (22 persons). The antigen gave no untoward reactions and proved to be safe when given orally in doses of 25 to 150 mg. Paratyphoid B antigen was characterized by a marked immunization activity and stimulated formation of specific paratyphoid O-, K- and H-agglutinins and antibodies of the IgA,- IgG,- and IgM-classes.
在一小群志愿者（22人）中研究了通过单阶段抗原提取获得的含有O、K和H抗原复合物的副伤寒制剂的反应原性和免疫效果。该抗原未引起不良反应，口服25至150毫克剂量时被证明是安全的。副伤寒B抗原具有显著的免疫活性，可刺激特异性副伤寒O、K和H凝集素以及IgA、IgG和IgM类抗体的形成。
