Juchet A, Guilhem M, Brémont F, Rancé F, Dutau G
Unité de Pneumo-Allergologie Infantile, Hôpital Purpan, Toulouse.
Rev Mal Respir. 1999 Apr;16(2):235-40.
Climate therapy is often proposed for children with severe allergic asthma which remains uncontrolled in spite of adapted treatment. The beneficial effects of climate therapy are related to the reduced allergenic load and to the fact that mites do not survive at high altitudes. Less exposure to allergens leads to improved respiratory function, decreased bronchial hyperreactivity and lower levels of total and specific IgE as well as markers of inflammation. These different actions combine to produce a lower prevalence of asthma at higher altitudes. Other advantages of climate therapy is related to better management of care by a multidisciplinary team. This in turn enables: a combined medial and paramedical approach to stablize the asthma with minimal effective doses of drug therapy; the development of a specific educational program aimed at improving therapeutic compliance; and an individualized education adapted to the learning problems which are often important in these children. The problems of the child being separated from his/her parents and the risk of recurrence after returning home must also be addressed and can generally be prevented by simple precautions.
气候疗法通常适用于尽管接受了适当治疗但仍未得到控制的重度过敏性哮喘儿童。气候疗法的有益效果与变应原负荷降低以及螨虫在高海拔地区无法存活这一事实有关。减少接触变应原可改善呼吸功能,降低支气管高反应性,降低总IgE和特异性IgE水平以及炎症标志物水平。这些不同的作用共同导致高海拔地区哮喘患病率较低。气候疗法的其他优势与多学科团队对护理的更好管理有关。这反过来又能够:采用医学和辅助医疗相结合的方法,以最小有效剂量的药物治疗稳定哮喘;制定旨在提高治疗依从性的特定教育计划;以及根据这些儿童中通常很重要的学习问题进行个性化教育。还必须解决儿童与父母分离的问题以及回家后复发的风险,并且通常可以通过简单的预防措施来预防。